From your point of view, which project would be the best cancer research project avaible?
I want to contribute my CPU time on the most effective project for cancer research.

World Community Grid's Help Conquer Cancer, hands down.

Gets my vote too. It is well run and you can target that area specifically. Most of the protein folding projects have relavence but are not targeted like the WCG cancer project.

But after reading the details information about the project, HCC is more like a project which improves the X-ray crystallography process. Rather than trying to discover a cure for cancer.

I'm not sure there is a 'best' project for cancer, but WCG is certainly one of them. HCC is only one on WCG. Another is the Human Proteome Folding project, which also overlaps with cancer. I think the broader way to look at cancer with BOINC projects is which ones help directly or indirectly with protein folding. All of those projects help conquer cancer, but none really directly: they help with anything that predicts protein structure, which also, by definition, helps to find cures for diseases, including of course, cancer. Almost all of my projects are protein folding projects. I give to them for the same reason you give for cancer: they help directly find cures for all known diseases. My signature below tells which ones I've chosen for protein folding.

What kind of disease is Einstein@Home curing?

I guess I will just crunch for HCC and put Rosetta and SIMAP as backup projects, in case of HCC runs out of work.

Thanks for the help guys.

No way to pick the best. Only History can do that. So "spread the love". Help them all.

That would be the best option. However, I only have limited CPU power, an E2160 and an E6750 (the E6750 won't be up untill March next year). So I guess I would focus on one or two projects at the moment.

With WCG, you can pick one or more projects, but set set it to pull from other projects if your primary/ies run out of work.

With me WCG get's a double time slice. They do a lot of good work. HCC, like the previous Help Defeat Cancer, seems like a project with a set run. I get the impression that the data will not expand, and they plan to finish this year. Still, they may get another Cancer project. There are so many kinds of cancer, so many causes, and so many aspects that there will projects for years to come. Also, WCG chooses good projects. The HIV and Dengue Fever projects do docking modeling for hundreds of potential pharmaceuticals, and those are two widespread diseases. The HPF project gets very high resolution imaging of protein docks on cells of many diseases, which can be uses for docking modeling for numerous bacteria and viruses. Also, keep in mind the Clean Energy Project. Many pollutants from coal burning, as well as waste from producing plastics and electronics, are carcinogenic. Finding a cheap, clean way to make electronics....

SIMAP is not directly cancer research, but is useful. They catalog "protein homologues", or similar proteins. Basically, it's this: Say you are researching a plant. It's closely related to wild wheat strains. You are doing this because a mold is killing cultivated wheat in your country, but the mold is most deadly to three of the five cultivars used in agriculture. Therefore, you know there is a genetic resistance. You've also found many wild strains are resistant, hence your study. Your molecular biologists have found seven proteins in the wild strain of unknown function. You consult your protein homologue database. You find that the amino acid chains that make three of these proteins are very similar to chains that make known anti-microbial proteins in other grains, but with a few deletions and insertions. You now know that these three proteins are the ones to study first, as they are the most promising. When you find that one or more of these work against your mold problem, you sequence the DNA based on the amino acid chain, splice it into a harmless bacteria, and you now have a defense against the mold threatening your country's agriculture. (Until the bacteria you've altered turns into a flesh-eating pandemic, turning your once beautiful and prosperous country into a desolate forsaken zone and wiping out all human life on your continent as punishment for playing G~d. Then end. )

That's the value of SIMAP. It benefits many genetic and molecular biology projects across all fields.

You know, I wouldn't put all of my crunch time to just one project. You already have a pretty impressive line-up on your signature. Rosetta nearly always has work, and so does WCG and Poem that you have already crunched for. I would reccomend putting those three as your primary projects: that give you 8 hrs/day/core. That's pretty boffo no matter how you look at it. And they are all protein folding related. When your new host comes online, you can bone up on others in your quiver. Remember that Simap only has work for short periods each month, so it is really only at best a good back up at certain perioids. I reccomend three primaries because you never know when one or even two will be offline for an extended period. That will keep you busy forever.

Docking is now online (no doubt another one you can count on), Tanpaku will be within the next few months (they apparently had a server crash, no idea why they've taken so long to get back up), and Proteins will be back up in the next week or so. There's lots of protein projects to be had for the taking.

I agree that WCG does good work (although I'm looking more towards projects with sustainability in mind) but it would be helpful if they played nicer with BAM. Also, I have to wonder why they take their site down everytime the update stats... It's kind of annoying, and not too helpful to combined stats sites since they only refresh twice a day. I realize that they're quite a bit larger in terms of users than other projects, but SETI keeps realtime stats and they have more users than WCG. With IBM backing them, I should think that server power wouldn't be an issue. Perhaps there is some other reason?

I don't think the "crunch for other WCG subprojects" would be helpful, if he's looking to specify his volunteered CPU time in one area... I currently have this off, and when there's no work from the subprojects I've selected, I get work from other BOINC projects.

Even with a single core PIII, you can crunch for an unlimited number of projects. BOINC will spread the love evenly for you (over the long term).

Assuming the resource share is the same on all projects.